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PI3Kγ ligand 1

Ligand for Target Protein for PROTAC

PI3Kγ ligand 1 is a selective ligand for phosphoinositide 3-kinase gamma (PI3Kγ), utilized in the development of proteolysis-targeting chimeras (PROTACs). This compound effectively engages with PI3Kγ, facilitating targeted protein degradation. Its biological activity makes it valuable for research applications in cancer therapeutics and immunology, particularly in elucidating PI3K signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2769753-45-7
Applications	Ligand for Target Protein for PROTAC
Formula	C₂₆H₂₉N₅O₃S
Molecular Weight	491.61
SMILES	NCCCN(C1CC1)S(C2=CC=C(C3=CN=C(N)C(C4=CC(CCNC5=O)=C5C=C4)=C3)C=C2)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.