Fig. 1 · Structure
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PI4KIIIbeta-IN-11
PI4KB Inhibitor
PI4KIIIbeta-IN-11 is a potent inhibitor of the enzyme PI4KIIIβ, exhibiting a mean pIC50 value of at least 9.1. This compound is instrumental in studying the biological mechanisms associated with RNA viruses and Plasmodium falciparum, making it valuable for research related to infectious diseases and potential therapeutic targets. Its ability to selectively inhibit PI4KIIIβ highlights its significance in advancing our understanding of these complex disease pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2365241-79-6 |
| Applications | PI4KB Inhibitor |
| Formula | C33H39N7O3 |
| Molecular Weight | 581.71 |
| SMILES | CN1C(C2=CC=CC(CNC3=CC(C(C)(O)C)=NC4=C(C5=CC(C(N(C)[C@@H](C)CO)=O)=C(C=C5)C)C(C)=NN34)=C2)=NC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.