PI4KIIIbeta-IN-9

Catalog No.: A16270

PI4KIIIβ inhibitor

PI4KIIIbeta-IN-9

PI4KIIIbeta-IN-9 Chemical Structure

CAS NO. 1429624-84-9

PI4KIIIbeta-IN-9 is a potent PI4KIIIbeta inhibitor (IC50 of 7 nM) and is >140-fold selective over PI3Kgamma and >20-fold selective over PI3Kδ, and shows no inhibition of vps34 at concentrations up to 20 uM.

Availability: In stock

Package Price Qty
1 mg
$100.00
5 mg
$270.00
10 mg
$405.00
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Biological Activity

PI4KIIIbeta-IN-9 is a potent PI4KIIIbeta inhibitor (IC50 of 7 nM) and is >140-fold selective over PI3Kgamma and >20-fold selective over PI3Kδ, and shows no inhibition of vps34 at concentrations up to 20 uM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.51 mL 102.55 mL 205.09 mL
0.5 mM 4.1 mL 20.51 mL 41.02 mL
1 mM 2.05 mL 10.25 mL 20.51 mL
5 mM 0.41 mL 2.05 mL 4.1 mL

*The above data is based on the productmolecular weight 487.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16270
Actions Inhibitor
CAS No. 1429624-84-9
Formula C23H25N3O5S2
M. Wt 487.59
Solubility DMSO
Purity >98%
SMILES CC1=C(SC(=N1)NC(=O)C2CCCC2)C3=CC(=C(C=C3)OC)S(=O)(=O)NC4=CC=C(C=C4)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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