Fig. 1 · Structure

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PI5P4Ks-IN-3

PI5P4K Inhibitor

PI5P4Ks-IN-3 is a covalent inhibitor targeting PI5P4K, exhibiting IC50 values of 1.34 μM for PI5P4Kα and 9.9 μM for PI5P4Kβ. This compound demonstrates potential utility in the study of phosphoinositide signaling pathways and cellular processes influenced by PI5P4K activity. Although it shows weak cellular activity, it serves as a valuable tool for dissecting the biochemical role of PI5P4K in various research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2471969-07-8
Applications PI5P4K Inhibitor
Formula C32H31N7O2
Molecular Weight 545.63
SMILES
CC(C=C1)=CC=C1N2C3=NC=NC(NC4=CC(NC(C5=CC=C(C=C5)NC(/C=C/CN(C)C)=O)=O)=CC=C4)=C3C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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