Fig. 1 · Structure
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Picolinamide
PARS Inhibitor
Picolinamide is a selective inhibitor of Poly(ADP-ribose) synthetase (PARS) and has demonstrated efficacy in modulating PARS activity in various biological models. By inhibiting PARS, picolinamide plays a crucial role in the study of cellular responses to DNA damage and the regulation of cellular energy metabolism. This compound is widely utilized in research focusing on neurodegeneration, cancer biology, and cellular stress responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1452-77-3 |
| Applications | PARS Inhibitor |
| Formula | C6H6N2O |
| Molecular Weight | 122.13 |
| Synonyms | 2-Picolinamide |
| SMILES | O=C(C1=NC=CC=C1)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.