Documents & Downloads

Picrasidine J

KLK-10/ERK Inhibitor

Picrasidine J is a selective inhibitor of KLK-10 protease and the ERK signaling pathway. It demonstrates significant anti-migratory and anti-invasive activities by upregulating E-Cadherin and ZO-1 while downregulating β-catenin and Snail. Additionally, it reduces KLK-10 expression and inhibits ERK phosphorylation. Picrasidine J is primarily utilized in research aimed at preventing metastasis in head and neck squamous cell carcinoma (HNSCC).

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	100234-62-6
Applications	KLK-10/ERK Inhibitor
Formula	C₁₄H₁₄N₂O₂
Molecular Weight	242.27
SMILES	OC1=CC=CC2=C1NC3=C2C(OC)=CN=C3CC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.