Fig. 1 · Structure
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PIK-108
p110/p110δ Inhibitor
PIK-108 is a selective allosteric inhibitor targeting p110β and p110δ, acting independently of ATP binding. It exhibits robust inhibition of these phosphoinositide 3-kinases, influencing signaling pathways involved in cell proliferation and survival. PIK-108 is widely utilized in research related to cancer biology and immune responses, making it a valuable tool for investigating therapeutic strategies in related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 901398-68-3 |
| Applications | p110/p110δ Inhibitor |
| Formula | C22H24N2O3 |
| Molecular Weight | 364.44 |
| SMILES | O=C1C=C(N2CCOCC2)OC3=C(C(NC4=CC=CC=C4)C)C=C(C)C=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.