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$0.00 Biological Activity
Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.67 mL | 108.33 mL | 216.66 mL |
| 0.5 mM | 4.33 mL | 21.67 mL | 43.33 mL |
| 1 mM | 2.17 mL | 10.83 mL | 21.67 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.33 mL |
*The above data is based on the productmolecular weight 461.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17375 |
|---|---|
| Actions | Antagonist |
| CAS No. | 2062-78-4 |
| Formula | C28H29F2N3O |
| M. Wt | 461.55 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | R 6238; R-6238; R6238; Pimozide; Orap; Opiran. |
| SMILES | O=C1N(C2CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)C5=CC=CC=C5N1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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