Fig. 1 · Structure
Documents & Downloads
PIN1 inhibitor 3
PIN1 Inhibitor
PIN1 Inhibitor 3 is a selective inhibitor of prolyl isomerase PIN1, exhibiting a dissociation constant (KD) of 25 nM and an IC50 of 150 nM. This compound serves as a valuable tool for investigating the role of PIN1 in various cellular processes and is particularly relevant in cancer research. Additionally, PIN1 Inhibitor 3 can be employed as a ligand in the synthesis of Proteolysis Targeting Chimeras (PROTACs), enabling targeted protein degradation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3039570-04-9 |
| Applications | PIN1 Inhibitor |
| Formula | C35H37N7O2 |
| Molecular Weight | 587.71 |
| SMILES | CC1=CC=CC=C1C2(CC2)C(NC(C(NC(CC3)CCN3C)=O)CC(N=N4)=CN4C(C=C5)=CC=C5C(C=C6)=CC=C6C#N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.