Fig. 1 · Structure
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(-)-Pinocembrin （l-Pinocembrin)
Anti-mycobacterium Drug
(-)-Pinocembrin targets Mycobacterium tuberculosis, demonstrating significant anti-mycobacterial activity with IC50 values of 1.11 mg/mL during the dormant phase and 1.21 mg/mL during the active phase. Additionally, it exhibits notable antiproliferative effects across various cancer cell lines, including THP-1, A549, Panc-1, HeLa, and MCF7, with IC50 values ranging from 1.88 to 11.00 mg/mL. This compound is a valuable tool for research in tuberculosis and cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 206660-42-6 |
| Applications | Anti-mycobacterium Drug |
| Formula | C15H12O4 |
| Molecular Weight | 256.25 |
| SMILES | O=C1C[C@H](C2=CC=CC=C2)OC3=CC(O)=CC(O)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.