Fig. 1 · Structure
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PIP4K-IN-a131
PIP4Ks Inhibitor
PIP4K-IN-a131 is an inhibitor of PIP4K lipid kinases, demonstrating IC50 values of 1.9 μM for purified PIP4K2A and 0.6 μM for PIP4Ks. This compound exhibits selective cytotoxicity in cancer cells by simultaneously inhibiting PIP4Ks and disrupting mitotic pathways. PIP4K-IN-a131 is particularly valuable in cancer research, enabling studies on the mechanistic roles of lipid kinases in tumor biology and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2055405-95-1 |
| Applications | PIP4Ks Inhibitor |
| Formula | C20H13N3 |
| Molecular Weight | 295.34 |
| SMILES | N#C/C(C1=CNC2=C1C=CC=C2)=C\C3=CC=CC4=C3C=CN=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.