Fig. 1 · Structure

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PIP5K1α-IN-1

PIP5K1α Inhibitor

PIP5K1α-IN-1 is a potent inhibitor of phosphatidylinositol 4-phosphate 5-kinase type I α (PIP5K1α), exhibiting an IC50 of 0.46 μM. This compound is utilized in research to explore the role of PIP5K1α in cellular signaling pathways, particularly those involving phosphoinositides. Its inhibition can provide insights into various biological processes and may have therapeutic implications in diseases linked to dysregulated phosphoinositide metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3063813-76-0
Applications PIP5K1α Inhibitor
Formula C29H36N4O3
Molecular Weight 488.62
SMILES
CC(C1=C(C=CC2=C1CC[C@@]3([H])C(C)(CCC[C@]23C)C)OCC4=CN(N=N4)C5=CC([N+]([O-])=O)=CC=C5)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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