Fig. 1 · Structure

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PIP5K1C-IN-1

PIP5K1C Inhibitor

PIP5K1C-IN-1 is a selective inhibitor of the phosphatidylinositol-4,5-bisphosphate 5-kinase type 1 gamma (PIP5K1C) with an IC50 of 0.80 nM. This compound demonstrates low systemic clearance in mouse models, indicating its potential for in vivo use. PIP5K1C-IN-1 is primarily utilized in research focused on cancer and chronic pain, providing insights into the role of PIP5K1C in these conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3060954-15-3
Applications PIP5K1C Inhibitor
Formula C20H20ClN5O
Molecular Weight 381.86
SMILES
O=C(N1CC2=C(C31CCC3)C(C(N4)=CC5=C4C=C(Cl)C=C5)=NN2)NC6CC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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