Fig. 1 · Structure
Documents & Downloads
Pipamperone dihydrochloride
5-HT2A/D4 Antagonist
Pipamperone dihydrochloride is a potent antagonist of the 5-HT2A (pKi=8.2) and D4 (pKi=8.0) receptors, derived from the butyrophenone class. It exhibits low-affinity antagonism at the D2 receptor (pKi=6.7) and is known to influence neurotransmitter systems, contributing to its antipsychotic effects. This compound is utilized in research focused on mental health disorders, including autism-related behavioral conditions and Alzheimer's disease.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2448-68-2 |
| Applications | 5-HT2A/D4 Antagonist |
| Formula | C21H32Cl2FN3O2 |
| Molecular Weight | 448.40 |
| Synonyms | Floropipamide dihydrochloride; McN-JR 3345 dihydrochloride; R 3345 dihydrochloride |
| SMILES | O=C(C1(N2CCCCC2)CCN(CCCC(C3=CC=C(F)C=C3)=O)CC1)N.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.