Fig. 1 · Structure
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Pipecuronium bromide
Neuromuscular Blocker
Pipecuronium bromide functions as a long-acting nondepolarizing steroidal neuromuscular blocker, acting primarily as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR). With a dissociation constant (Kd) of 3.06 μM, it effectively inhibits neuromuscular transmission, making it valuable for facilitating intubation and maintaining muscle relaxation during surgical procedures. Its applications also extend to research examining neuromuscular function and pharmacological studies involving skeletal muscle.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Blocker |
| CAS Number | 52212-02-9 |
| Applications | Neuromuscular Blocker |
| Formula | C35H62Br2N4O4 |
| Molecular Weight | 762.70 |
| SMILES | C[C@@]1([C@H]2OC(C)=O)[C@](C[C@@H]2N3CC[N+](C)(C)CC3)([H])[C@@](CC[C@]4([H])[C@@]5(C[C@H](N6CC[N+](C)(C)CC6)[C@@H](OC(C)=O)C4)C)([H])[C@]5([H])CC1.[Br-].[Br-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.