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Piperafizine B

Antitumor Agent

Piperafizine B acts as an antitumor agent with demonstrated cytotoxicity against various cell lines, including Moser cells, P388 cells, and Vincristine-resistant P388 cells, with IC50 values of 23.8, 22.6, and 23.7 μg/mL, respectively. This compound exhibits synergistic effects when combined with Vincristine, enhancing its cytotoxic potential and showing efficacy in alleviating leukemia in mouse models. Piperafizine B is a valuable tool for cancer research, particularly in exploring combination therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	74720-33-5
Applications	Antitumor Agent
Formula	C₁₈H₁₄N₂O₂
Molecular Weight	290.32
SMILES	O=C(/C(NC/1=O)=C/C2=CC=CC=C2)NC1=C/C3=CC=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.