Fig. 1 · Structure
Documents & Downloads
Pirfenidone-d5
Stable Isotope
Pirfenidone-d5 is a deuterium-labeled derivative of pirfenidone, primarily utilized as a stable isotope in chemical research. This compound exhibits antifibrotic properties by reducing the production of CCL2 and CCL12 in fibrocyte cells. Additionally, pirfenidone-d5 demonstrates a growth-inhibitory effect and lowers TGF-β2 protein levels in human glioma cell lines, while also possessing anti-inflammatory activities. It is a valuable tool for studying fibrotic disease mechanisms and evaluating therapeutic strategies in cancer and inflammation research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1020719-62-3 |
| Applications | Stable Isotope |
| Formula | C12H6D5NO |
| Molecular Weight | 190.25 |
| Synonyms | AMR69-d5 |
| SMILES | O=C1C=CC(C)=CN1C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.