PIT-1

Catalog No.: A79793
PI3K Inhibitor
PIT-1 is a selective inhibitor of phosphatidylinositol 3,4,5-trisphosphate (PIP3) that targets the PI3K/Akt signaling pathway. By inhibiting PIP3, PIT-1 effectively disrupts cancer cell survival and promotes apoptosis. This compound demonstrates significant antitumor activity in vivo, making it suitable for investigations into cancer therapeutics and signaling pathways involved in oncogenesis.
Grouped product items
Size Price Stock Qty
5mg
$25.00
In stock
10mg
$30.00
In stock
25mg
$60.00
In stock
50mg
$90.00
In stock
100mg
$140.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPIT-1 is a selective inhibitor of phosphatidylinositol 3,4,5-trisphosphate (PIP3) that targets the PI3K/Akt signaling pathway. By inhibiting PIP3, PIT-1 effectively disrupts cancer cell survival and promotes apoptosis. This compound demonstrates significant antitumor activity in vivo, making it suitable for investigations into cancer therapeutics and signaling pathways involved in oncogenesis.
Product Information
Catalog NumA79793
FormulaC14H10ClN3O4S
Molecular Weight351.76
CAS Number53501-41-0
SMILESO=C(NC(NC1=CC([N+]([O-])=O)=CC(Cl)=C1O)=S)C2=CC=CC=C2
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