Fig. 1 · Structure
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Pitnot-2
Pitstop 2 Inactive Analog
Pitnot-2 is an inactive analog of the clathrin inhibitor Pitstop 2, designed to serve as a negative control in research. Its primary mechanism involves inhibition of clathrin-mediated endocytosis, allowing researchers to assess the specificity and functional effects of active compounds. This reagent is particularly useful in studies investigating cellular uptake mechanisms and the role of clathrin in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1576239-29-6 |
| Applications | Pitstop 2 Inactive Analog |
| Formula | C20H13BrN2OS |
| Molecular Weight | 409.30 |
| SMILES | BrC(C=C1)=CC=C1/C=C2SC(NC3=CC=CC4=C3C=CC=C4)=NC\2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.