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Pitolisant-d5 hydrochloride

Isotope-Labeled Compounds

Pitolisant-d5 hydrochloride is a deuterium-labeled analog of Pitolisant hydrochloride, functioning primarily as a selective nonimidazole inverse agonist at the human histamine H3 receptor (Ki=0.16 nM). This compound enables researchers to study the pharmacokinetics and metabolism of Pitolisant in biological systems. Its isotopic labeling provides a valuable tool for various applications in drug development, including receptor binding studies and metabolic pathway investigation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2740634-42-6
Applications	Isotope-Labeled Compounds
Formula	C₁₇H₂₂D₅Cl₂NO
Molecular Weight	337.34
Synonyms	Ciproxidine-d5 hydrochloride; BF 2649-d5 hydrochloride
SMILES	ClC(C=C1)=CC=C1C([2H])C([2H])([2H])C([2H])([2H])OCCCN2CCCCC2.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.