PK11007
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | PK11007 is an anti-p53 drug that stabilizes wild type and mutant p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. It exerts antitumor functions not only via reactivating p53 but also via other cellular mechanisms, such as increase of cellular ROS to toxic levels and activation of the UPR. |
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Catalog Num | A16833 |
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Formula | C6H5ClN2O4S |
Molecular Weight | 236.63 |
CAS Number | 38275-34-2 |
SMILES | CS(=O)(=O)C1=NC=C(C(=N1)C(=O)O)Cl |
Synonyms | PK 11007, PK-11007 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 46 mg/mL (194.39 mM) | |
Water | 46 mg/mL (194.39 mM) | ||
Ethanol | 23 mg/mL (97.19 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 42.26 mL | 211.3 mL | 422.6 mL |
0.5 mM | 8.45 mL | 42.26 mL | 84.52 mL |
1 mM | 4.23 mL | 21.13 mL | 42.26 mL |
5 mM | 0.85 mL | 4.23 mL | 8.45 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2