PK11007

Catalog No.: A16833
p53 activator
PK11007 is an anti-p53 drug that stabilizes wild type and mutant p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. It exerts antitumor functions not only via reactivating p53 but also via other cellular mechanisms, such as increase of cellular ROS to toxic levels and activation of the UPR.
Grouped product items
Product Name Price Stock Qty
PK11007 5mg
$50.00
In stock
PK11007 10mg
$80.00
In stock
PK11007 50mg
$250.00
In stock
PK11007 100mg
$420.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription PK11007 is an anti-p53 drug that stabilizes wild type and mutant p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. It exerts antitumor functions not only via reactivating p53 but also via other cellular mechanisms, such as increase of cellular ROS to toxic levels and activation of the UPR.
Product Information
Catalog Num A16833
Formula C6H5ClN2O4S
Molecular Weight 236.63
CAS Number 38275-34-2
SMILES CS(=O)(=O)C1=NC=C(C(=N1)C(=O)O)Cl
Synonyms PK 11007, PK-11007
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 46 mg/mL (194.39 mM)
Water 46 mg/mL (194.39 mM)
Ethanol 23 mg/mL (97.19 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 42.26 mL 211.3 mL 422.6 mL
0.5 mM 8.45 mL 42.26 mL 84.52 mL
1 mM 4.23 mL 21.13 mL 42.26 mL
5 mM 0.85 mL 4.23 mL 8.45 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy PK11007 | PK11007 Supplier | purchase PK11007 | PK11007 cost | PK11007 manufacturer | order PK11007 | PK11007 distributor | buy 38275-34-2 | 38275-34-2 Supplier | purchase 38275-34-2 | 38275-34-2 cost | 38275-34-2 manufacturer | order 38275-34-2 | 38275-34-2 distributor