Fig. 1 · Structure
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PKC-IN-6
Tyrosine and Serine Kinases Inhibitor
PKC-IN-6 (Compound 21) is a selective inhibitor of tyrosine and serine kinases, targeting key players such as PKC-α, PKC-δ, and EGF-R. It demonstrates inhibitory activity with IC50 values of 240 μM for PKC-α and >500 μM for both PKA and PKC-δ. With its potential to modulate kinase activity, PKC-IN-6 is a valuable tool for cancer research, facilitating the understanding of signaling pathways involved in tumorigenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 152460-10-1 |
| Applications | Tyrosine and Serine Kinases Inhibitor |
| Formula | C16H15N5 |
| Molecular Weight | 277.33 |
| SMILES | NC1=CC(=C(C=C1)C)NC2=NC=CC(=N2)C3=CC=CN=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.