PKC-theta inhibitor
Catalog No.: A19712
PKC-θ inhibitor
PKC-theta inhibitor is a selective PKC-θinhibitor, with an IC50 of 12 nM.
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Biological Activity
| Description | PKC-theta inhibitor is a selective PKC-θinhibitor, with an IC50 of 12 nM. | ||
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| Targets |
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Product Information
| Catalog Num | A19712 |
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| Formula | C20H25F3N6O3 |
| Molecular Weight | 454.45 |
| CAS Number | 736048-65-0 |
| SMILES | FC(F)(F)OC1=CC=CC=C1CNC2=NC=C([N+]([O-])=O)C(NCC3CCC(CN)CC3)=N2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 85 mg/mL (187.04 mM) | |
| Water | Insoluble | ||
| Ethanol | 28 mg/mL (61.61 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22 mL | 110.02 mL | 220.05 mL |
| 0.5 mM | 4.4 mL | 22 mL | 44.01 mL |
| 1 mM | 2.2 mL | 11 mL | 22 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
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