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PKHB1

Peptide Mimic

PKHB1 is a thrombospondin-1 peptide mimic that exerts antitumor effects primarily through mitochondrial dysfunction. It promotes the production of reactive oxygen species (ROS), triggers intracellular calcium accumulation, and activates calcium-dependent apoptotic pathways in breast cancer cells. Additionally, PKHB1 facilitates immune system activation by inducing immunogenic cell death, making it a valuable tool for research into cancer therapeutics and immunology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1505523-99-8
Applications	Peptide Mimic
Formula	C₆₈H₁₀₅N₁₇O₁₂S
Molecular Weight	1384.73
Synonyms	txCD47
SMILES	C([C@@H](C(N[C@H](C(N[C@H](CCCCN)C(O)=O)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](CCCCN)N)=O)CCCNC(=N)N)=O)=O)=O)C(C)C)=O)[C@H](C)C)=O)CCSC)=O)C=3C=4C(NC3)=CC=CC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.