Fig. 1 · Structure
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PKM2 activator 5
Cat. No.
A77406
CAS
796092-26-7
PKM2 Activator
PKM2 activator 5 is a selective activator of pyruvate kinase M2 (PKM2) with an AC50 value of 0.316 µM. This compound modulates the metabolic pathways of cancer cells by enhancing PKM2 activity, thereby promoting a shift from aerobic to anaerobic metabolism. PKM2 activator 5 has applications in cancer research, particularly in studies focused on metabolic reprogramming and the development of novel therapeutic strategies targeting cancer metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 796092-26-7 |
| Applications | PKM2 Activator |
| Formula | C18H19FN2O6S2 |
| Molecular Weight | 442.48 |
| SMILES | O=S(N1CCN(S(=O)(C2=CC=C(OCCO3)C3=C2)=O)CC1)(C4=CC=CC(F)=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.