Fig. 1 · Structure

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PKM2-IN-4

Cat. No. A77422 CAS 2996165-24-1

PKM2 Inhibitor

PKM2-IN-4 is a selective inhibitor of pyruvate kinase M2 (PKM2), exhibiting an IC50 of 0.35 μM. This compound is known to regulate pyruvate-dependent respiration and promotes mitochondrial H2O2 production, impacting the efficiency of the electron transport system. It serves as a valuable tool in research focused on metabolism, cancer biology, and oxidative stress.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2996165-24-1
Applications PKM2 Inhibitor
Formula C15H17BrClNO3Se
Molecular Weight 453.62
SMILES
BrC1=C([Se][N+]2=C1C=C(C(OC)=O)C=C2)C3(CCCCC3)O.[Cl-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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