Fig. 1 · Structure

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PKM2-IN-9

Cat. No. A77423 CAS 498568-75-5

PKM2 Inhibitor

PKM2-IN-9 is a selective inhibitor of pyruvate kinase M2 (PKM2), achieving an inhibition rate of 75% at a concentration of 50 μM. This compound is of significant interest in cancer research, as it regulates metabolic pathways essential for tumor growth and survival. PKM2-IN-9 can be utilized to explore the role of PKM2 in cellular processes and as a potential therapeutic target in various types of cancer.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 498568-75-5
Applications PKM2 Inhibitor
Formula C24H22N4O2
Molecular Weight 398.46
SMILES
O=C(C1=CC=CC=C1)NCC2=NC3=C(N2CC(NC4=CC=CC(C)=C4)=O)C=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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