PKMYT1-IN-9 is a selective inhibitor of PKMYT1, demonstrating an IC50 of 4.4 nM. This compound shows significantly higher selectivity for PKMYT1 compared to WEE1, which has an IC50 of 32.4 μM. PKMYT1-IN-9 has been characterized by its antitumor activity, making it a valuable tool in cancer research and therapeutic studies targeting checkpoint pathways.
PKMYT1-IN-9 is a selective inhibitor of PKMYT1, demonstrating an IC50 of 4.4 nM. This compound shows significantly higher selectivity for PKMYT1 compared to WEE1, which has an IC50 of 32.4 μM. PKMYT1-IN-9 has been characterized by its antitumor activity, making it a valuable tool in cancer research and therapeutic studies targeting checkpoint pathways.
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