Fig. 1 · Structure
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PKR activator 5
Cat. No.
A77415
CAS
2761226-35-9
PKR Activator
PKR Activator 5 (Compound 18) is a potent activator of pyruvate kinase R (PKR), exhibiting an AC50 of 28 nM. This compound enhances PKR activity, which plays a critical role in regulating glycolysis and energy metabolism. PKR Activator 5 is valuable for research applications aimed at understanding the metabolic pathways associated with PKR and their implications in cancer and metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2761226-35-9 |
| Applications | PKR Activator |
| Formula | C23H19ClFN9O |
| Molecular Weight | 491.91 |
| SMILES | CC1=NN(C(CNC(NCC2=NC=NN2C3=CC4=C(C=C3)C=CC=N4)=O)=N1)C5=CC=C(C(F)=C5)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.