Fig. 1 · Structure

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Pks13-TE inhibitor 2

Pks13-TE Inhibitor

Pks13-TE inhibitor 2 is a potent inhibitor of the 13-Thioesterase enzyme Pks13-TE, with an IC50 value of 1.30 μM. This compound exhibits significant anti-tuberculosis activity, effective against both drug-sensitive and drug-resistant Mycobacterium tuberculosis strains, with a minimum inhibitory concentration ranging from 0.0039 to 0.0078 μg/mL. Pks13-TE inhibitor 2 is a valuable tool for research into multidrug-resistant and extensively drug-resistant tuberculosis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3031462-75-3
Applications Pks13-TE Inhibitor
Formula C22H19NO5
Molecular Weight 377.39
SMILES
O=C(C1=C2OC3=CC=C(OCN(C4CCCC4)C5)C5=C31)OC6=C2C=CC(O)=C6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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