Fig. 1 · Structure

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PLAP-IN-1

PLAP Inhibitor

PLAP-IN-1 is a potent inhibitor of placental alkaline phosphatase (PLAP), exhibiting an IC50 of 32 nM. This compound demonstrates high selectivity, showing no detectable inhibition of tissue non-specific alkaline phosphatase (TNAP) activity. It is suitable for research applications focused on exploring the role of PLAP in various physiological and pathological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2857113-78-9
Applications PLAP Inhibitor
Formula C25H21Cl2N3O5
Molecular Weight 514.36
SMILES
ClC1=C(OC)C(Cl)=CC(C2=CC=CC(C[C@@H](NC(C3=NNC(C4=CC=C(C)O4)=C3)=O)C(O)=O)=C2)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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