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PLK1-IN-10

Name: PLK1-IN-10
Brand: Adooq Bioscience
SKU: A56908
Availability: OutOfStock

Cat. No. A56908 CAS 2991469-21-5

PLK1 Inhibitor

PLK1-IN-10 is a potent inhibitor of the polo-like kinase 1 (PLK1) polo-box domain. This compound disrupts the interaction between PLK1 and the cell division regulator protein PRC1, leading to a reduction in the expression of the CDK1-Cyclin B1 complex. Additionally, PLK1-IN-10 interacts with glutathione (GSH), increasing cellular oxidative stress and promoting apoptosis. Its applications include cancer research and studies on cell cycle regulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2991469-21-5
Applications	PLK1 Inhibitor
Formula	C₂₃H₂₂FN₃O₄S
Molecular Weight	455.50
SMILES	CN(C)CCN(C1=O)C(C2=CC=C(S(NCC3=CC=C(F)C=C3)(=O)=O)C4=CC=CC1=C42)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.