Fig. 1 · Structure

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PLK1-IN-7

Cat. No. A56911 CAS 2938910-96-2

PLK1 Inhibitor

PLK1-IN-7 is a highly effective inhibitor of Polo-like kinase 1 (PLK1), demonstrating an IC50 of 0.66 nM. This compound exhibits significant antiproliferative and antitumor activities, making it a valuable tool for cancer research. Its ability to modulate PLK1 activity supports investigations into cell cycle regulation and potential therapeutic applications in oncology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2938910-96-2
Applications PLK1 Inhibitor
Formula C24H24F4N8O2
Molecular Weight 532.49
SMILES
FC(F)(OC(C=CC(N1CCN(C)CC1)=C2)=C2NC3=NC=C4C(C5=C(C=C4)C(C(N)=O)=NN5CCF)=N3)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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