Fig. 1 · Structure

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Plm IV inhibitor-1

Plm IV Inhibitor

Plm IV Inhibitor-1 is a selective inhibitor of plasmepsin IV (Plm IV), exhibiting notable potency with an IC50 of 0.25 µM. This compound demonstrates additional inhibitory activity against Plm I, Plm II, and Cathepsin D, making it suitable for studies on protease modulation in biological systems. Plm IV Inhibitor-1 is primarily utilized in research focused on malaria and related parasitic diseases, facilitating the exploration of therapeutic strategies targeting Plm IV.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1539276-41-9
Applications Plm IV Inhibitor
Formula C37H51N5O3
Molecular Weight 613.83
SMILES
CCCN(CCC)C(C1=CC(C(N[C@H]([C@H](O)CNC(C)(C2=CC=CC=N2)C)CC3=CC=CC=C3)=O)=CC(N4CCCCC4)=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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