PLX8394
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | PLX8394 is a next-generation, orally available, small-molecule BRAF inhibitor with IC50 values of 3.8 nM, 14 nM and 23 nM for BRAF(V600E), WT BRAF and CRAF respectively. It has potential antineoplastic activity. |
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Catalog Num | A16840 |
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Formula | C25H21F3N6O3S |
Molecular Weight | 542.53 |
CAS Number | 1393466-87-9 |
SMILES | O=S(N1C[C@H](F)CC1)(NC2=CC=C(F)C(C(C3=CNC4=NC=C(C5=CN=C(C6CC6)N=C5)C=C43)=O)=C2F)=O |
Synonyms | PLX 8394, PLX-8394 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 96 mg/mL (176.95 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.43 mL | 92.16 mL | 184.32 mL |
0.5 mM | 3.69 mL | 18.43 mL | 36.86 mL |
1 mM | 1.84 mL | 9.22 mL | 18.43 mL |
5 mM | 0.37 mL | 1.84 mL | 3.69 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2