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PMO-G

Spherical-shape Polymeric Micelles

PMO-G is a spherical-shaped polymeric micelle that exhibits enhanced skin permeation. This reagent has demonstrated the ability to significantly increase dystrophin levels, achieving up to a 50-fold enhancement in the abdominal muscles of mdx mice. PMO-G is particularly relevant for research applications focused on Duchenne muscular dystrophy, providing valuable insights into potential therapeutic strategies for this condition.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2708274-72-8
Applications	Spherical-shape Polymeric Micelles
Formula	C₄₃H₄₆ClN₈O₇P
Molecular Weight	853.30
SMILES	CN(C)P(OC[C@H](C1)O[C@@H](N2C3=NC(NC(C(C)C)=O)=NC(OCCC4=CC=C(C=C4)[N+]([O-])=O)=C3N=C2)CN1C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)(Cl)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.