Fig. 1 · Structure
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Pneumolysin-IN-1
PLY inhibitor
Pneumolysin-IN-1 is a selective inhibitor of Pneumolysin (PLY) with an IC50 of 3.1 µM. It acts primarily as a pore-blocking agent, disrupting the pathogenic effects associated with PLY's virulence. This compound is useful for investigating the mechanisms of infection and pathogenesis caused by Streptococcus pneumoniae, providing valuable insights into therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 330842-49-4 |
| Applications | PLY inhibitor |
| Formula | C23H16Cl2N2O4 |
| Molecular Weight | 455.29 |
| SMILES | O=C1NC(N(C2=CC(C)=CC(C)=C2)C(/C1=C/C3=CC=C(C4=C(Cl)C=C(Cl)C=C4)O3)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.