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pNP-ADPr

Colorimetric Substrate

pNP-ADPr is a colorimetric substrate specifically designed for the continuous assays of poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3). This reagent enables the study of the activity and regulation of poly(ADP-ribose) polymerase (PARP) enzymes, facilitating research into cellular processes such as DNA repair and stress response mechanisms. Its utility in enzyme activity assays makes it an essential tool for investigating the functional roles of ADP-ribosylation in various biological contexts.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	939028-75-8
Applications	Colorimetric Substrate
Formula	C₂₁H₂₆N₆O₁₆P₂
Molecular Weight	680.41
Synonyms	ADP-ribose-pNP
SMILES	O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]1COP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](OC5=CC=C([N+]([O-])=O)C=C5)O4)(O)=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.