Fig. 1 · Structure
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PNPLA3 modifier 1
Pnpla3 Modifier
PNPLA3 Modifier 1 is a small molecule that targets the patatin-like phospholipase domain-containing protein 3 (PNPLA3), exhibiting a geometric mean EC50 of 4.9 nM. This compound serves as a potent modifier of PNPLA3 activity, making it invaluable for research focused on lipid metabolism and hepatic disorders. It is particularly relevant for studies investigating the role of PNPLA3 in non-alcoholic fatty liver disease and other metabolic conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3036158-95-6 |
| Applications | Pnpla3 Modifier |
| Formula | C16H19ClF2N2O4S |
| Molecular Weight | 408.85 |
| SMILES | O=S1(N(CCCC1)[C@H]2CN(CC(F)(C2)F)C(OC3=CC=C(C=C3)Cl)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.