Fig. 1 · Structure
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pNPS-DHA
DHA-ethanolamide Derivative
pNPS-DHA is a DHA-ethanolamide derivative recognized for its antiallergic properties. It effectively inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in murine models, demonstrating its potential for allergy research. Additionally, pNPS-DHA exhibits significant anti-degranulating activity in RBL-2H3 mast cells, with an IC50 of 15 μM, making it a valuable tool for studies focused on mast cell-related allergic responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2454246-25-2 |
| Applications | DHA-ethanolamide Derivative |
| Formula | C28H36N2O5S |
| Molecular Weight | 512.66 |
| SMILES | CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(NS(=O)(C1=CC=C([N+]([O-])=O)C=C1)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.