PNU-120596

Catalog No.: A11203

Nicotinic (α7) Receptor Modulator

PNU-120596

PNU-120596 Chemical Structure

CAS NO. 501925-31-1

PNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors.

Availability: In stock

Package Price Qty
10 mg
$60.00
25 mg
$120.00
50 mg
$220.00
100 mg
$390.00
10mM * 1mL in DMSO
$60.00
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Biological Activity

PNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors.
Targets
α7 nAChR
216 nM(EC50)
In vitro (25°C) DMSO 62 mg/mL (198.89 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (3.2 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.08 mL 160.4 mL 320.8 mL
0.5 mM 6.42 mL 32.08 mL 64.16 mL
1 mM 3.21 mL 16.04 mL 32.08 mL
5 mM 0.64 mL 3.21 mL 6.42 mL

*The above data is based on the productmolecular weight 311.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11203
Actions Modulator
M. Wt 311.72
Formula C13H14ClN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 501925-31-1
Synonyms PNU120596
SMILES CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl

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