Fig. 1 · Structure
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PNU-140975
KATP Channel Activator
PNU-140975 is a potent activator of KATP channels, demonstrating significant biological activity in the modulation of energy balance. This compound has been shown to activate KATP channels in isolated arcuate neurons, leading to reductions in body weight in rat models. Its utility in research includes studies focused on metabolic disorders and the mechanisms underlying energy homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 179474-69-2 |
| Applications | KATP Channel Activator |
| Formula | C3H9N5O2 |
| Molecular Weight | 147.14 |
| Synonyms | BVT.3531 |
| SMILES | O=C(CN(C(NN)=N)N)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.