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PNU-177864 hydrochloride

Catalog No.: A59551
Dopamine D3 Receptor Antagonist
PNU-177864 hydrochloride is a potent and selective antagonist of the dopamine D3 receptor. This compound is known to influence phospholipid metabolism in vivo and exhibits potential anti-schizophrenia activity. It serves as a valuable tool for researchers exploring the role of dopamine receptors in neurological disorders and for developing therapeutic strategies.
PNU-177864 hydrochloride 1783978-03-9 Dopamine D3 Receptor Antagonist
Grouped product items
Size Price Stock Qty
5mg
$25.00
In stock
10mg
$40.00
In stock
25mg
$65.00
In stock
50mg
$95.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPNU-177864 hydrochloride is a potent and selective antagonist of the dopamine D3 receptor. This compound is known to influence phospholipid metabolism in vivo and exhibits potential anti-schizophrenia activity. It serves as a valuable tool for researchers exploring the role of dopamine receptors in neurological disorders and for developing therapeutic strategies.
Product Information
Catalog NumA59551
FormulaC18H22ClF3N2O3S
Molecular Weight438.89
CAS Number1783978-03-9
SMILESO=S(C1=CC=C(OC(F)(F)F)C=C1)(NC2=CC=C(CCNCCC)C=C2)=O.[H]Cl
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GPCR/G Protein > Dopamine Receptors