Fig. 1 · Structure
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PNU-22394 hydrochloride
5-HT Agonist
PNU-22394 hydrochloride is a potent agonist for the 5-hydroxytryptamine (5-HT) receptors, specifically engaging the 5-HT2C and 5-HT2A receptor subtypes with Ki values of 6.1 nM and 10 nM, respectively. This compound is valuable for studying the roles of 5-HT in neurobiology and its implications in various psychiatric disorders. Its selective action on serotonin receptors makes it a useful tool for investigating serotonin signaling pathways and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 15923-42-9 |
| Applications | 5-HT Agonist |
| Formula | C13H17ClN2 |
| Molecular Weight | 236.74 |
| SMILES | CN1C(CCNCC2)=C2C3=C1C=CC=C3.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.