Fig. 1 · Structure
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PNU-96415E
D4/5-HT2A Antagonist
PNU-96415E is a selective antagonist of the dopamine D4 receptor and the 5-HT2A serotonin receptor. It demonstrates potential antipsychotic efficacy, making it a valuable tool in the study of neuropsychiatric disorders. Researchers can utilize PNU-96415E to explore its effects on dopaminergic and serotonergic signaling pathways in various preclinical models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 170856-41-4 |
| Applications | D4/5-HT2A Antagonist |
| Formula | C21H27Cl2FN2O |
| Molecular Weight | 413.36 |
| SMILES | FC1=CC=C(N2CCN(CCC3C4=CC=CC=C4CCO3)CC2)C=C1.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.