Fig. 1 · Structure
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Pociredir hydrochloride
EED Inhibitor
Pociredir hydrochloride is a potent inhibitor of Embryonic Ectoderm Development (EED) with oral bioactivity. This compound has been shown to induce HbF protein expression in both cellular and murine models. Pociredir hydrochloride is valuable for research into various hemoglobinopathies, particularly sickle cell disease and β-thalassemia, offering insights into potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2490676-19-0 |
| Applications | EED Inhibitor |
| Formula | C22H19ClFN5O2 |
| Molecular Weight | 439.87 |
| Synonyms | FTX-6058 hydrochloride |
| SMILES | CC1=NC=CC=C1C2=CC(OC3)=C(NCC4=C(F)C=CC5=C4[C@@H]3CO5)N6C2=NN=C6.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.