POI ligand-4

Name: POI ligand-4
Brand: Adooq Bioscience
SKU: A56907
Rating: 5 (288 reviews)

Catalog No.: A56907

PLK1 Ligand

POI ligand-4 is a selective ligand for Polo-like kinase 1 (PLK1), serving as a crucial building block in the development of PROTACs. This compound facilitates targeted degradation of PLK1, exemplified in the synthesis of PROTAC PLK1 Degrader-3. It is instrumental in advancing research on cancer therapies and PLK1-related pathways.

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Biological Activity

Description	POI ligand-4 is a selective ligand for Polo-like kinase 1 (PLK1), serving as a crucial building block in the development of PROTACs. This compound facilitates targeted degradation of PLK1, exemplified in the synthesis of PROTAC PLK1 Degrader-3. It is instrumental in advancing research on cancer therapies and PLK1-related pathways.

Product Information

Catalog Num	A56907
Formula	C24H41N8O10P
Molecular Weight	632.60
CAS Number	1403265-80-4
SMILES	O=P(O)(O)O[C@H](C)[C@@H](C(N)=O)NC([C@H](CO)NC([C@H](CC1=CN=CN1)NC([C@H](CC(C)C)NC([C@H]2NCCC2)=O)=O)=O)=O

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