Fig. 1 · Structure
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POLA1 inhibitor 1
POLA1 Inhibitor
POLA1 Inhibitor 1 is a potent inhibitor of POLA1, designed for oral administration. This compound demonstrates significant antitumor activity across various tumor histotypes, including efficacy against Adarotene-resistant cell lines. It serves as a valuable tool for research in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2217671-41-3 |
| Applications | POLA1 Inhibitor |
| Formula | C26H27NO4 |
| Molecular Weight | 417.50 |
| SMILES | O=C(O)/C=C/C1=CC=C(C2=CC=C(O)C(C34CC5CC(C4)CC(C5)C3)=C2)C(/C=N/O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.