Fig. 1 · Structure

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Poloxamer 407 (F127)

LPL Receptor Inhibitor

Poloxamer 407 (F127) is a nonionic surfactant that primarily acts as a lipoprotein lipase (LPL) receptor inhibitor. It enhances the water solubility of various fluorescent dye AM esters, including Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8 AM, and Quest Rhod-4 AM. With its low toxicity at low concentrations, Poloxamer 407 serves as a valuable tool in cellular studies and assays that require improved dye solubility for effective visualization and analysis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 9003-11-6
Applications LPL Receptor Inhibitor
Molecular Weight 12600(Average)
Synonyms PEG-PPG-PEG; 12600 (Average Mn)
SMILES
CC.[H(OCH2CH2)x(OCH2CH)y(OCH2CH2)zOH].[CH3]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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