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Poloxin is a non-ATP competitive Polo-like Kinase 1 (PLK1) inhibitor that targets the polo-box domain, with an IC50 of appr 4.8 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.63 mL | 168.15 mL | 336.3 mL |
| 0.5 mM | 6.73 mL | 33.63 mL | 67.26 mL |
| 1 mM | 3.36 mL | 16.82 mL | 33.63 mL |
| 5 mM | 0.67 mL | 3.36 mL | 6.73 mL |
*The above data is based on the productmolecular weight 297.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11524 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 321688-88-4 |
| Formula | C18H19NO3 |
| M. Wt | 297.35 |
| Solubility | DMSO |
| Purity | >98% |
| SMILES | O=C(C(C(C)C)=C/1)C=C(C)C1=N/OC(C2=CC=CC=C2C)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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